Screening for trisomy 13, 18 and 21 by analysis of free circulating foetal DNA
What is NIPS?
During pregnancy, the placenta releases fetal DNA that can be detected in the mother's blood. If DNA from chromosomes 13, 18 or 21 is present in abnormally high quantities, this means that the fetus has a high probability of having trisomy for one of these chromosomes. NIPS thus makes it possible to detect trisomy 13, 18 or 21 in the fetus, by means of a simple blood test taken by the mother-to-be. On request, the sex of the fetus can be determined and indicated on the report.
➡ This is a risk-free test for the fetus.
What are the indications?
NIPS can be performed during every pregnancy in the absence of ultrasound anomalies. The NIPS test does not replace regular ultrasound monitoring of the pregnancy, whatever the result.
In practice?
Your gynecologist will prescribe this test for you. NIPS can be carried out from the 10th week of amenorrhea (SA), ideally from 12 SA, but it can be prescribed right up to the end of the pregnancy.
➡ It is performed using a simple blood test.
There's no need to fast.
Make sure you have the prescription, the consultation certificate and the signed consent form (documents given to you by your doctor).
You can carry out your non-invasive prenatal screening without an appointment in one of our 85+ laboratories. You can also carry out your screening at the address of your choice, at no extra charge, via PICKEN DOHEEM.
• (+352) 27 321
• On the website bionext.lu/rdv
• With MYLAB-app (iOS et Android)
FAQ : useful information about the test
How long does it take to receive the results?
It takes 10 days.
Is the test reimbursed?
If you are affiliated to the CNS and the test is prescribed by a doctor, the test is covered. If you are not affiliated to the CNS or the test is prescribed by a midwife, the test is not covered.
To find out more about available tests and prices, click on the button below:
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How does the test perform?
The test is highly sensitive (>99.9%) and specific (99.9%) for detecting trisomy 13, 18 and 21. However, only amniocentesis can provide a definitive diagnosis. It will be proposed to you depending on the results of the NIPS.
How do I interpret the results?
Your doctor will inform you of the results. If the result is negative, this means that the test did not detect fetal trisomy 13, 18 or 21. Your pregnancy will continue to be monitored as usual. If the result is positive, the presence of trisomy (13, 18 or 21) is probable. A positive result must be confirmed by an invasive prenatal diagnosis such as amniocentesis. If the result is inconclusive or uninterpretable, this does not mean that the risk of trisomy is high, but simply that, due to a technical problem or an insufficient quantity of fetal DNA, the test has failed. It is then necessary to repeat the analysis on a new sample, usually 14 days after the first test.
